The creature Bio Rex was designed by the Keerlon Corporation. His creation is the result of genetic manipulation research that was outlawed on Earth centuries ago. He was created from the DNA of a fossilized dinosaur egg, but altered to have human-level intelligence and increased strength. Genetic design allowed for the development of higher brain functions equivalent to that of a human.
However, before he even got to race, he had to endure several press conferences, interviews, public appearances, and was constantly under constant public scrutiny. Eventually, his patience reached a breaking point and his fiery temper caused some rather embarrassing bad press for the Keerlon Corporation. They distanced themselves from Bio Rex, who still intended to enter the Grand Prix. During his first year he as a 'new species' was determined to prove he was superior to human. However the following year he entered mainly to satisfy his ravenous appetite for mammoth ribs.
- A character very similar to him appears being arrested by Captain Falcon in the manual of the first F-Zero.
|Introduced in F-Zero|
|Captain Falcon - Dr. Stewart - Pico - Samurai Goroh|
|Introduced in F-Zero X|
|Antonio Guster - Mrs. Arrow - Baba - Beastman - Billy - Bio Rex - Black Shadow - Blood Falcon - Dr. Clash - Draq - Mr. EAD - Gomar & Shioh - Jack Levin - James McCloud - Jody Summer - John Tanaka - Kate Alen - Leon - Michael Chain - Mighty Gazelle - Octoman - Roger Buster - Silver Neelsen - The Skull - Super Arrow - Zoda - Super Falcon (through cheat code)|
|Introduced in F-Zero: Maximum Velocity|
|Megan - Mickey Marcus - Jane B. Christie - Nichi - Lord Cyber - Alexander O'Neil - Blitz Wagner - Kent Akechi - Kumiko - Professor Yazoo Jr.|
|Introduced in F-Zero GX/AX|
|Phoenix - Princia Ramode - QQQ - Don Genie - Terry "Digi-Boy" Getter - Dai Goroh - Dai San Gen - Lily Flyer - PJ - Deathborn - Spade|
|Introduced in F-Zero: GP Legend|
|Rick Wheeler - Lucy Liberty - Misaki Haruka - Lisa Brilliant|
|Introduced in F-Zero Climax|
|Berserker - Clank Hughes - Death Soldier|
| Racer #14|
| Racer #15|
| Racer #16|
|Characters of F-Zero|